A ROLE OF THE NSE4 KLEISIN AND NSE1/NSE3 KITE SUBUNITS IN THE ATPASE CYCLE OF SMC5/6

Abstract The SMC (Structural Maintenance of Chromosomes) complexes are composed of SMC dimers, kleisin and kleisin-interacting (HAWK or KITE) subunits.Mutual interactions of these subunits constitute Full Panel Bed the basal architecture of the SMC complexes.In addition, binding of ATP molecules to the SMC subunits and their hydrolysis drive dynami